STUDIES ON THE APPLICATION OF PROMIN THROUGH THE MOUTH
1956 Volume 25 Issue 3 Pages 143-146
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1956 Volume 25 Issue 3 Pages 143-146
1) I examined the decomposition of promin, and observed that promin did not decompose itself in an incubator (37°C), then I decomposed promin by HCl in artificial juice and Na2CO3 in artificial enteroic juice, the formerr was almost decomposed at 40 min., and the later at 60 min.
2) I poured promin into stomach, and observed the quantity of excretion of promin in urine, which showed the highest excretion of promin at the 3rd-4th hour. In comparison with oral medication and intravenose, the former is 23-51% of latter.
3) I examined the influence of promin given through the stomach of rabbits on the quantity of Ca in blood and urine, and Fe in blood. I recognized that the quantity of them increased slightly.
