STUDIES ON THE INOCULATION TO DIFFERENT ANIMALS OF LEPROSY BACILLI
(The 3rd Report) On the Susceptibility of Cats and Nutrias with M. Leprae Murium
1956 Volume 25 Issue 3 Pages 147-158
Details
1956 Volume 25 Issue 3 Pages 147-158
After the intraperitoneal inoculation of murine leprosy bacillus suspension to cats and nutrias, the intraperitoneal fluid was collected, of which migrating cells, phagocytotic cells and extra- cellular acid-fast bacilli were investigated. Moreover, distribution of bacilli were examined by autopsy.
The results of examination of susceptibility of these animals to the murine bacillus were as following.
1) The bacilli inoculated into the intraperitoneal cavity produced no infectious finding after 2 months, though in some cases they presented a picture of multiplication in the testis. After staying 2 months in cats, the bacilli still kept infectiousness to white rats.
2) Inoculation of the murine bacilli into the intraperitoneal cavity of nutrias produced no murine leprosy.
3) Multiplication of bacilli in the migrating cells of intraperitoneal cavity could not be observed not only in cats and nutrias, but also in white rats.
4) The intraperitoneal migrating cells were not different in the properties between cats or nutrias and white rats. But the migrating stadium of monocytes and neutrophile leucocytes were different in cats and nutrias and in white rats.
