癩と結核の免疫学的関連性に就いて

第4篇 全篇を通しての考按並に結論

抄録

It has generally been accepted that B.C.G. vaccination induces positive lepromin reaction, which can be considered as to indicate certain grade of immunity to leprosy.
Based on these findings, certain workers have tried to give B.C.G. vaccination for the pro-phylaxis of leprosy.
Taking these facts into consideration, the author made studies on the immunological rela-tionship between leprosy and tuberculosis. Animal experiments were carried out to investigatethe influence of tuberculous infection on the development of murine leprosy and vice versa.
As described in the previous reports, the existence of certain grades of cross-immunitybetween tuberculosis and murine leprosy could be observed.
In these experiments, phenol-killed vaccine, liquid paraffine vaccine and B.C.G. were tested asto give resistance to the infection, of which B.C.G. seemed to exhibit a certain grade of pro-phylactic effects against murine leprosy.