Repura
Online ISSN : 2185-1352
Print ISSN : 0024-1008
ISSN-L : 0024-1008
PROPHYLAXIS OF LEPROSY BY MEANS OF DRIED BCG VACCINE (THE FIRST REPORT)
Ken YANAGISAWANozomu ASAMIShigerori ISHIWARA
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1957 Volume 26 Issue 2 Pages 70-76

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Abstract
Lepromin allergy was pursued after BCG vaccination regarding it as an indirect expression of leprous immunity. The results obtained in two separate populations of school children showed clearly the fact that BCG vaccination could convert more than half of the total objects to positive to lepromin test made 8 to 11 weeks after vaccination. For instance, in the first case where the vaccination was made by the scarification method, the positive conversion rate was 56.5 per cent in 11 weeks, and in the second case of intracutaneous vaccination it was 77.4 per cent in 8 weeks. In addition, it was found that a high correlation is kept between the lepromin reaction and the tuberculin reaction in connection with size of redness. The two populations of children employed for the present study is now undergoing the further survey of both kinds of allergy.
As far as the present study is concerned, the authors consider that BCG vaccination is effective for the prophylaxis of leprosy.
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