Repura
Online ISSN : 2185-1352
Print ISSN : 0024-1008
ISSN-L : 0024-1008
BIOCHEMICAL STUDIES OF THE MURINE LEPROSY BACILLUS (Part 2)
ON THE RESPIRATORY METABOLISM OF THE MURINE LEPROSY BACILLUS
Tonetaro ITORyuzo SONODA
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1957 Volume 26 Issue 5 Pages 255-260

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Abstract
This paper deals with the influences of many substrates known as nutritious elements or accelerating substances and of organ and murine leproma extracts of rats upon the respiration of the murine leprosy bacillus which had been treated with trypsin and centrifuged.
The results obtained are below:
1) Seventeen substrates, such as glycelin, succinate and vitamin B12, did not accelerate the respiration of the bacillus in single addition. When liver or testis extract inactivated 60°C30min. was combined with succinate, the respiration is accelerated.
2) Untreated murine serum prevented the respiration. Liver extract, when inactivated, produced no influence. Testis extract showed acceleration of which intensity was stronger whed untreated than when inactivated. Acceleration was observed when extracts of murine leproma in liver, testis or subcutaneous tissue were applied. In these extracts inactivation produced more intense acceleration than untreated.
Attention should be paid to the fact that extracts of various organs and murine leproma accelerate the respiration of the murine leprosy bacillus.
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