抄録
Normal healthy school children (6-8 years of age) with negative lepromin and tuberculin reactions, were inoculated with dried BCG vaccine by the intracutaneous method or scarification and the reactions examined after 8-11 weeks or 1 year.
1) Regardless of the method of inoculation, the lepromin reaction was 70.8-72.6% positive and the tuberculin reaction was 82.9-84.0% positive after 1 year. A considerably high correlation was maintained between the size of the erythema induced by both reaction tests at all stages following inoculation of BCG.
2) Injection of 0.1% lactate solution as a placebo instead of BCG vaccine resulted in a 46.7% positive lepromin reaction and 51.1% positive tuberculin reaction after 1 year. It is suggested that is due to the fact that both the lepromin and tuberculin reactions are allergy reactions.
