1959 Volume 28 Issue 6 Pages 301-310
Blocking the cells of reticuloendothelial system with colloidal suspension of carbon black was carried, for the purpose of analysing the mechanism on infection of murine leprosy according to development of murine leprosy when the symbioses between bacilli and murine leprosy cells were alternated.
One hundred and four mice used in this experiment were divided into eight groups. The course of blocking was observed for five months before and after inoculation of murine leprosy bacilli.
The results were following:
1. A marked inhibition of development of murine leprosy was showed both in the group injected with carbon black before the inoculation and the group blocked before and after the inoculation.
2. A marked inhibition was showed in a group in which the blocking was carried before the 15th day after the inoculation.
3. A slight inhibition was observed in the group in which the blocking was carried after the 20th day of the inoculation.
4. A marked acceleration was observed in mice group injected with a mixture of carbon black and bacilli.
