STUDIES ON THE CHEMOTHERAPY OF LEPROSY
(XXIII) Onset Suppressing Action of Ciba 1906, Griseofulvin, Zygomycin A and Several Drugs in Murine Leprosy
1961 Volume 30 Issue 3-4 Pages 159-162
Details
1961 Volume 30 Issue 3-4 Pages 159-162
A number of screening tests concerning various drugs for murine leprosy have been performed by the authors. The present report deal with several drugs since 1959 up to this day.
1) Ciba 1906 was unable to suppress the onset of the disease.
2) Griseofulvin (7-chloro-4. 6. 2'-trimethoxy-6', -methyl-gris-2, -en-3. 4'-dione) indicated no suppressing nor healing effect.
3) Zygomycin A showed no effect by oral administration, but brought up a sign of slight suppression by subcutaneous injection.
4) P-Ethoxyphenyl-methyl-dithiocarbamate (No.255 TAKEDA) and P-Ethoxyphenyl-benzyl-dithioc-arbamate (No.258 TAKEDA) were ineffective, either administered separately or combined with DDS.
