Effects of processing Kombu on lipid metabolism in genetically diabetes mice

Abstract

　　We investigated the effects of dietary supplementation with softened kombu on lipid metabolism in genetically type 2 diabetic mice (KK/Ta). KK/Ta mice were randomly divided into three groups and fed a high-fat diet containing cellulose (CO group), dried kombu (IN group) and softened kombu (SO group) corresponding to 5% total dietary fiber for 68 days. The total abdominal fat mass was lower in the SO group than that of the IN group. The serum cholesterol concentrations were significantly lower in the both IN and SO groups than in the CO group, and the SO group was also lower than that of the IN group. These results indicate that dietary supplementation with softened kombu attenuate dyslipidemia in diabetic mice.