Abstract
The probability of survival of pediatric aplastic anemia after hematopoietic stem cell transplantation (allo-HSCT) has become excellent, but only limited data are available regarding health condition and social status. In this study, to obtain fundamental information about pediatric aplastic anemia, we performed a surveillance study for aplastic anemia patients who received allo-HSCT and became 20 years or older. Replies were obtained from 12 out of 18 patients (66.7％). Excluding 2 patients with Fanconi anemia, 1 of 10 patients had a body height of less than －2SD. Eight of 10 females had menses. Among 3 married females, 4 pregnancies were reported in 2 patients, and 3 pregnancies resulted in live healthy births. Performance status (PS) of 9 out of the 12 patients was 0. Our study showed that pediatric aplastic anemia patients could have good health condition and social status, but some patients suffered low PS or amenorrhea. To establish optimal treatment for pediatric aplastic anemia, a long-term follow-up system is required.
