Prevalence and associated characteristics of aponeurotic ptosis among a general population in Japan

抄録

  Background: Ptosis is caused mainly by age-related degeneration of the aponeurosis caused by lifestyle-related diseases. Some patients with ptosis complain of stiff shoulders and headaches. There have been few actual epidemiological investigations of aponeurotic ptosis and these symptoms. We aimed to find their prevalence and associated characteristics of ptosis in Japanese general population.
  Methods: The target population consisted of 1004 volunteers who took part in the 2016 Iwaki Health Promotion Project. We administered a questionnaire, took blood samples, took physical measurements, and measured marginal reflex distance（ MRD-1） in each participant. The relationship between survey items（ age, gender, difficulty in raising eyelids, headache, stiff shoulders, hypertension, diabetes, dyslipidemia, and body mass index［ BMI］） and eyelid droop was examined statistically.
  Results: The prevalence of ptosis in this study was 15.4%. Ptosis prevalence correlated with elderly people 65 years or older （odds ratio. 3.07, 95% CI: 2.02–4.66）, male sex （odds ratio. 0.29, 95% CI: 0.20–0.43）, hypertension （odds ratio. 1.68, 95% CI: 1.11–2.54） and dyslipidemia（ odds ratio. 1.51, 95% CI: 1.02–2.23）.
  Conclusions: The present results suggested that hypertension, dyslipidemia and male sex were thought to be the risk factors of aponeurotic ptosis in Japanese general population.