Abstract
Generally, it has been considered that the enterprise performance or the profit, is increased due to the rationalization of processes of manufacturing and distribution, which is the forward integration, the backward integration or the both integration, in addition to the superiority of products. Furthermore, it has been also expected that the effect of the integration is to be enhanced due to the information investment. Therefore, on major medicine manufacturers in our country, the investment effects of machinery and information are ex post facto assessed based on securities reports and also the relationship between the investment effects and the undertaking matter including business architecture together with activities of related enterprises.