Abstract
Aging as a physiological part of life is the cumulative result of oxidative damage to cells which derives from aerobic metabolism. Insufficient tissue oxygenation occurs in a wide range of physiological and pathological conditions and reactive oxygen species are physiological products of aerobic life and their accumulation affects aging. Considering that Italian population is aging quickly, social, rehabilitation andexercise training programs than would prevent diseases improvingthe quality of life,has to deal with human physiology.