IEEJ Transactions on Electronics, Information and Systems
Online ISSN : 1348-8155
Print ISSN : 0385-4221
ISSN-L : 0385-4221
<Biomedical Engineering;>
Development of Multi-Analytes DNA Microchip by Using 3-D Nanoprototyping Fabrication Method
Daisuke FukuokaTomohiro IkedaYuichi Utsumi
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2009 Volume 129 Issue 2 Pages 272-276

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Abstract
The importance of the micro fluidics systems for high throughput post-genome analysis has increasing more and more. We proposed and fabricated an integrated 6 microchip capillary electrophoresis units in a small area of 30mm×30mm for high throughput DNA analysis. The design of the structure was performed using fluid dynamics of electrophoresis simulation to improve DNA separation resolution. As a result, narrow width of micro channel at the corner was adapted. As for the simple fabrication method of the microchip, we developed the PMMA structure of micro fluid channel using lithography, molding and fusion bonding techniques. It was demonstrated that the proposed integrated structure of micro channels results in a good performance of the on-chip DNA separation in a small one unit area of 9mm×9mm.
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© 2009 by the Institute of Electrical Engineers of Japan
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