International Heart Journal
Online ISSN : 1349-3299
Print ISSN : 1349-2365
ISSN-L : 1349-2365
Clinical Studies
Synchronization of the Flow and Pressure Waves Obtained With Non-Simultaneous Multipoint Measurements
Effects of the Cut-Off Frequencies for Breathing and Heartbeat on Blood Flow Analysis in the Fontan Circulation
Shinji GotoMasanori NakamuraKeiichi ItataniShohei MiyazakiNorihiko OkaTakashi HondaTadashi KitamuraTetsuya HoraiMasahiro IshiiKagami Miyaji
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2016 Volume 57 Issue 4 Pages 449-455


The use of measured data as boundary conditions renders hemodynamic simulations more patient-specific. However, synchronized acquisition of data at multiple locations is often difficult in clinical practice. This study proposes a method for resynchronizing measured data for use as boundary conditions for flow simulations using frequency analyses, and discusses the optimal cut-off frequency for differentiating cardiac and respiratory variation in hemodynamic data during resynchronization. To demonstrate the utility of the method, a Fontan circulation, which is the final palliative result with single-ventricle physiology, was used. The results suggest that it is optimal to set a cut-off frequency that gives a local minimum in the power spectrum that is slightly lower than the peak frequency of the heartbeat. Additionally, the total energy loss depended on the cut-off frequency, although the overall flow patterns appeared to be similar. The method is applicable to cardiovascular systems other than the Fontan circulation, where hemodynamic data with multifactorial fluctuations are required at various locations but simultaneous measurements are not possible.

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© 2016 by the International Heart Journal Association
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