抄録
The selective administration of dopamine, norepinephrine, epinephrine and isoproterenol, into the coronary sinus region of the dog heart produced so-called coronary sinus rhythm, indicating the appearance of deep inverted P waves and frequently accompanied by an acceleration of pacemaker activity of the coronary sinus region. These effects of catecholamines were not influenced by atropine and tetrodotoxin but were blocked by propranolol. The coronary sinus rhythm was easily produced by suppression of SA nodal pacemaker activity. Coronary sinus rhythm may be readily elicited if the coronary sinus area is excited by adrenergic stimuli or if the SA node is suppressed by cholinergic excitation.
