Platelet Aggregation and the Volume Distribution of Platelets in Spontaneously Hypertensive Rats

抄録

Dysfunction of the platelets was proven in SHR by ADP and collagen-induced aggregation, and platelet aggregation in response to collagen extracted from the aorta and mesenteric arteries of SHRSP and SHRSR was also less extensive. The volume distribution of platelets was found to be skewed to larger sizes in SHR, especially in SHRSP, and this finding indicated the possibility of the clinical application of examining the distribution of platelet volume for detecting vascular compli-cations.