Abstract
Lower glucose tolerance was observed not only in the hypertensive examinees but also in the normotensives with obvious family history of cerebral stroke, and this was similar to the findings obtained in adult SHR as well as in the prehypertensive SHR, indicating that a minute deviation of glucose metabolism detected by GTT might be related to the genetic desposition to hypertension. Serum cholesterol level was slightly decreased 1 hour after glucose administration both in humans and rats. This response may be the general biological phenomenon showing an intricate relation between glucose and cholesterol metabolisms. GTT is expected to be one of the parameters for predicting hypertension and cerebral stroke clinically and epidemiologically
