Abstract
Because 2, 3DPG is one of the main factors which are concerned with the affinity of Hb for oxygen and 3PG is the degrading metabolite of 2, 3DPG, there are three following possibilities in SHRSP: 1) in pulmonary tissues the diffusion of oxygen may be interfered to some extent (cf. results 1 & 2), 2) in peripheral tissues the less releasing of oxygen from Hb may cause oxygen deficiency (cf. results 3 & 4) and therefore, these findings may be the underlying factors which cause hypertension (cf. result 6), and 3) the inability of producing 2, 3DPG may result in the decreased tolerance under oxygen deficiency, and the process of production or degradation of 2, 3DPG in SHRSP must have some defects.
