Idiopathic Myocarditis Associated with T-Cell Subset Changes and Depressed Natural Killer Activity

Tsugiyasu KANDA; Shigeru OHSHIMA; Kazuo YUASA; Takashi WATANABE; Tadashi SUZUKI; Kazuhiko MURATA

doi:10.1536/ihj.31.741

Tsugiyasu KANDA, Shigeru OHSHIMA, Kazuo YUASA, Takashi WATANABE, Tadashi SUZUKI, Kazuhiko MURATA

著者情報

キーワード: Resolving myocarditis, CD4/CD8 ratio, NK cell activity

ジャーナルフリー

1990 年 31 巻 5 号 p. 741-744

DOI https://doi.org/10.1536/ihj.31.741

詳細

抄録

A 65-year-old man with idiopathic myocarditis is described. He was admitted with symptoms of acute heart failure. Examination revealed left ventricular hypokinesis. Results of an endomyocardial biopsy showed "resolving myocarditis". Immunological studies of the peripheral blood showed a low helper-suppressor (CD4/CD8) ratio on admission and depressed natural killer (NK) cell activity coincident with the onset of myocarditis. We considered that this immunological imbalance may have occurred during the progression of myocarditis to dilated cardiomyopathy.

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