抄録
The hemodynamic effects of propranolol at rest were studied in 13 patients with Fallot's tetralogy. After the infusion of propranolol into right ventricle, heart rate and blood pressure decreased in all cases, whereas there were no definite tendencies in changes of right ventricular pressure, its first derivative, and arterial oxygen saturation. The results obtained indicated that propranolol has little, if any, effects in relieving the right ventricular outflow tract obstruction in Fallot's tetralogy at rest. The changes of arterial oxygen saturation depend mainly on the changes of total peripheral resistance. It is concluded that the role of sympathetic activity in producing cyanosis at rest in Fallot's tetralogy is minimal.
