Abstract
In respect to the molecular targeting DDS, the interaction between cell tissue interface and nano-particle is quite important. DPD method is applied to the analysis of interaction between lipid bilayer and nano-particle. The DPD method can reproduce the lipid bilayer as almost same level as molecular dynamics simulation. According to the investigation on the effect of nano-particle movement, the control of the interaction duration between hydrophilic part and hydrophobic part is quite important to avoid the break-up or disturbance of lipid bilayer due to the nano-particle movement.
