International Journal of Biomedical Soft Computing and Human Sciences: the official journal of the Biomedical Fuzzy Systems Association
Online ISSN : 2424-256X
Print ISSN : 2185-2421
ISSN-L : 2185-2421
Stochastic Model of Actin-Myosin System, New Stochastic Resonance Inclined Rods Model Having Double Springs (DS-SIRM)
Hiroyuki MATSUURAMasahiro NAKANO
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JOURNAL OPEN ACCESS

2002 Volume 8 Issue 1 Pages 1-13

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Abstract

New Stochastic Inclined Rods Model(DS-SIRM)is proposed for understanding the movement of actin-myosin system in muscle. DS-SIRM has many inclined rods stood out from its body like myosin, and it moves always forward to one direction whenever those rods are independently vibratin. DS-SIRM can convert the thermal noise to the one directional motion by using stochastic resonance and inclined rods in random open fields. We estimated concretely the physical characteristics of DS-SIRM as a conceptual model of actin-myosin system. If SIRM have the radius r = 5nm and mass 10^-21kg like a myosin molecule, the estimated frequency of stochastic resonance which is nearly phonon frequency 10^11 rad /s. The amplitude of stochastic resonance is 2×10^-11 m. Moreover, physical work of this machine is about 10^-18 joules, which is nearly equal to the energy of 1ATP hydrolysis, and output is 10^-10 N/head. As a conclusion, we pointed out that actin myosin system in muscle utilized the random motion of water molecules for its movement.

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© 2002 Biomedical Fuzzy Systems Association
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