2024 年 22 巻 2 号 p. 50-56
The purpose of present study was to examine whether decreased temporal muscular activity after the removal of the temporalis muscle is related to the number of neural stem cells in hippocampal dentate gyrus in rats. Six rats in control group were incised and sutured in the temporal region, whereas each of six rats in unilateral- and bilateral-cut groups underwent removal of the right and both temporalis muscles, respectively, and were sutured. At 27 weeks postnatally, the numbers of Bromodeoxyuridine labelled cells in unilateral-cut and bilateral-cut groups were considerably lower than that in control group. The ratios of neurons to Bromodeoxyuridine labelled cells in unilateral-cut and bilateral-cut groups were considerably lower than that in control group. The findings of this study suggest that decreased temporal muscle activity is associated with fewer neural stem cells in hippocampal dentate gyrus.
