抄録
The rickets rat is a rat model of metabolic bone disease that displays deficient calcification of bone throughout the body. By placing an implant in the tibia of the rickets rat, the present research sought to : measure bone contact ratio with regard to bone healing around the implant as a result of differences in surface properties, examine crystallization of apatite using a micro X-ray diffraction and compare the compatibility of various implants. Bone contact ratio 4 weeks after implant placement was greater with a sandblasted implant (control group, 68.8±22.8% ; rickets group, 46.9±19.4%) than an anodic oxidation implant (control group, 64.7±20.7% ; rickets group, 36.6±17.9%). Similarly, 8 weeks after implant placement contact was greater with a sandblasted implant (control group, 80.2±12.9% ; rickets group, 61.1±18.1%) than an anodic oxidation implant (control group, 74.0±18.3% ; rickets group, 52.4±16.6%). Four and 8 weeks after implant placement, micro X-ray diffraction indicated a greater total amount of crystals for the sandblasted implant than the anodic oxidation implant in both the control and the rickets groups, and apatite with good crystallinity was detected.
