2010 Volume 8 Issue 3 Pages 162-166
Multiple myeloma is a relatively uncommon malignancy of plasma cell origin that often appears to have multicentric origins within the bone. A case of multiple myeloma with primary manifestation in the oral cavity is reported, presenting as a maxillary alveolar mass with mobility and loss of teeth. Roentgenographic examination demonstrated concomitant “punched-out” osteolytic jawbones and cranial lesions. Awareness of the maxillofacial manifestations of multiple myeloma is important for early detection of this disease, especially in patients with initial oral involvement that could well be the first indication of disease.