Synthesis and its DNA Detecting Ability of Fluorescent Modified β-cyclodextrins having Long Chain Connected by pyrene Unit

Noriaki MATSUMURA; Masami KAGAYA; Yoshihiko KONDO; Youichi AKAGAMI; Fumio HAMADA

doi:10.5188/ijsmer.16.16

Originals

Synthesis and its DNA Detecting Ability of Fluorescent Modified β-cyclodextrins having Long Chain Connected by pyrene Unit

Noriaki MATSUMURA, Masami KAGAYA, Yoshihiko KONDO, Youichi AKAGAMI ^†, Fumio HAMADA ^†

著者情報

キーワード: cyclodextrins, pyrene, ssDNA, dsDNA, linker, fluorescent spectra

ジャーナルフリー

2009 年 16 巻 1_2 号 p. 16-21

DOI https://doi.org/10.5188/ijsmer.16.16

詳細

抄録

Two kinds of pyrene modified β-cyclodextrins, which are different in linker parts to bind between β-cyclodextrin and pyrene unit, were synthesized. Those derivatives show different behavior for single and double strands of DNA, where short linker derivative shows no interaction for DNA, but longer linker derivative indicates there are something interaction for DNA by intercalating of pyrene unit.

責任著者(Corresponding author)

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