Fluorescent Molecular Recognition Systems of Terphenyl Modified β- and γ-Cyclodextrins

抄録

Terphenyl-modified, β- and γ-cyclodextrin analogues (1 and 2) have been prepared to investigate their fluorescent molecular sensor ability for organic guests, such as terpenoids or bile acids. These hosts show a pure monomer fluorescence with increasing or decreasing by accommodation of a guest. The extent of fluorescence variation with a guest is used to display the sensing ability of those host molecules. Host 1 detects smaller guests such as terpenoids with much higher sensitivity in a 10vol.-% dimethylsulfoxide (DMSO) aqueous solution than those of in a 20vol.-% DMSO aqueous solution. On the other hand, larger guests such as bile acids were detected with less sensitivity in a 20vol.-% DMSO aqueous solution by 1. The sensing ability of 2 for a guest examined was hardly effected by the solvent. The molecular sensing system combined with 1 and 2 could be useful method, because their binding behaviors for guests are different, in which the parameter values indicating the sensing ability obtained from 1 were almost positive, whereas the parame ter ones for 2 were negative.