Abstract
Introduction: Cold atmospheric plasma (CAP) is an effective disinfection and wound-care tool. We conducted the first clinical trial for plasma care® in Japan to evaluate bacterial load reduction.
Methods: Seven patients with chronic foot ulcers were treated with plasma care® for one week. Plasma care® was used once daily during dressing changes. Bacterial load was measured before and after treatment.
Results: Treatment with plasma care® reduced bacterial load in five patients, while two patients showed no changes. The treatment was safe with no adverse events. Although CAP exerted antibacterial effects, we observed no clear reduction in wound size during the observation period.
Conclusion: Plasma care® is safe and effective for bioburden reduction in patients with chronic foot ulcers.
