亜酸化窒素麻酔時の気管内チューブカフ内圧上昇緩和の工夫 : カフ内圧調整装置の試作

抄録

The pressure in endotracheal tube cuff increases during general anesthesia with nitrous oxide. High cuff pressures can be responsible for local ischemia of the tracheal mucosa, which may induce mucosal injury. In this study, we developed a prototype device to adjust cuff pressure, which can release the excessive gas mixture from the cuff through the bundled hollow silicone fibers into either atmosphere or a connected reservoir. When the device with or without the reservoir was used, diffusion rate of the gas through cuff membrane increased from 0.285 to 0.357 and 0.322ml/cmH 20/h, resulting in achievement of minimal increase in cuff pressure at incremental rate of 30% for 13 hours and 20% for 4 hours, respectively, as compared with 150% after 5 hours with the endotracheal tube alone. This novel device, with or without connection to the reservoir, would be useful in attaining the optimal cuff pressure for required hours for general anesthesia with nitrous oxide to avoid tracheal mucosal injury.