Abstract
It is said that proper antimicrobial use is dealt with from the viewpoint of infectious patients' safe and certain recovery and prevention of the appearance and spread of antibiotic-resistant bacteria as well as making efficient use of medical expenses, and particularly, proper management of antimicrobial use is an important problem from the aspect of economy as well. Therefore, I investigated how measures (a use application system of antiMRSA medicine / carbapenem-based medicine, a monitor system, a warning notice system) for the direction for management of antimicrobial use and the DPC system introduction may have influenced medicine costs. As a result, the quantity of carbapenem-based medicine consumed and the total amount of money used for the antimicrobial were reduced by half, though the total quantity of the antimicrobial agent consumed was almost constant for the investigation period. Furthermore, the average number of hospitalization days decreased, too.
It is thought that, from these factors, due to efforts for proper antimicrobial use, a change from broad-spectrum antimicrobials to narrow-spectrum as well as replacing expensive antimicrobials with cheaper products, etc. has resulted in progress in the selection of appropriate antimicrobials. I understood that the direction for management of antimicrobial use based on proper use results in a big cost cut effect on medicine costs.
