Industrial Health
Online ISSN : 1880-8026
Print ISSN : 0019-8366
ISSN-L : 0019-8366
CADMIUM ACCUMULATION IN LIVER AND KIDNEY OF RABBIT WITH SINGLE INJECTION
Masami KIMURANoriko OTAKI
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1975 Volume 13 Issue 4 Pages 203-210

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Abstract
The cadmium accumulation with a single injection was studied in rabbits. In-jected dose of cadmium was 3 mg per kg of body weight. The cadmium conentra-tions in liver and kidney were measured after 3 hours to 24 months. The liver cadmium reached the maximum concentration at the early stage (3 days-2 weeks), and then it decreased slowly. The kidney cadmium increased up to one year. Then, it retained a certain level (approximate 100 μg per g) for one more year. More than 80 per cent of the organ cadmium were found in the metallothionein fraction on Sephadex G-75 gel filtration.
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© National Institute of Occupational Safety and Health
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