Abstract
The erythrocyte, plasma and brain cholinesterase (ChE) activities of male rats and mice were determined using a simple colorimetric micromethod. In the normal male mice, the plasma ChE activity was 2.3 times higher than that of the erythrocyte. On the contrary, in the normal male rats, the erythrocyte ChE activity was 2.3 times higher than that of the plasma. The brain ChE activity was similar between rats and mice. The erythrocyte, plasma and brain ChE activities were decreased in both rats and mice exposed to diazinon and, however, this enzyme inhibition was most remarkable in the plasma of mice.