Industrial Health
Online ISSN : 1880-8026
Print ISSN : 0019-8366
ISSN-L : 0019-8366
Cholinesterase Activities in the Blood and Brain of Rats and Mice, as Determined by a Rapid Colorimetric Method
Katsumaro TOMOKUNITohru HASEGAWA
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1985 Volume 23 Issue 2 Pages 75-80

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Abstract
The erythrocyte, plasma and brain cholinesterase (ChE) activities of male rats and mice were determined using a simple colorimetric micromethod. In the normal male mice, the plasma ChE activity was 2.3 times higher than that of the erythrocyte. On the contrary, in the normal male rats, the erythrocyte ChE activity was 2.3 times higher than that of the plasma. The brain ChE activity was similar between rats and mice. The erythrocyte, plasma and brain ChE activities were decreased in both rats and mice exposed to diazinon and, however, this enzyme inhibition was most remarkable in the plasma of mice.
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© National Institute of Occupational Safety and Health
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