Reversible Cardiomyopathy as the Autonomic Involvement of Neuroleptic Malignant Syndrome

Masahiro OOMURA; Tadashi TERAI; Koichiro SUEYOSHI; Koji SHIGENO

doi:10.2169/internalmedicine.43.1162

Cardiovascular Diseases

Reversible Cardiomyopathy as the Autonomic Involvement of Neuroleptic Malignant Syndrome

Masahiro OOMURA, Tadashi TERAI, Koichiro SUEYOSHI, Koji SHIGENO

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Keywords: neuroleptic malignant syndrome, ventricular dysfunction, rhabdomyolysis, autonomic nervous system

JOURNAL OPEN ACCESS

2004 Volume 43 Issue 12 Pages 1162-1165

DOI https://doi.org/10.2169/internalmedicine.43.1162

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Abstract

Autonomic disturbance develops commonly in neuroleptic malignant syndrome (NMS). However, the association of cardiomyopathy is rare. Takotsubo-shaped cardiomyopathy is a unique reversible heart syndrome involving autonomic disturbance and mimicking myocardial infarction. We report a 63-year-old woman who developed Takotsubo-shaped cardiomyopathy during the course of NMS. Our case suggests the occurrence of reversible cardiomyopathy as the autonomic involvement of NMS.

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