Silico-Asbestosis that Responded to Steroid Therapy

Sakuo Hoshi; Yotaro Tamai; Atsushi Tamura; Hirofumi Ishida; Nozomi Yoshida; Chuhei Ogawa; Naoto Suzuki; Yasuyuki Sano; Yoshinori Kawabata

doi:10.2169/internalmedicine.45.1656

CASE REPORTS

Silico-Asbestosis that Responded to Steroid Therapy

Sakuo Hoshi, Yotaro Tamai, Atsushi Tamura, Hirofumi Ishida, Nozomi Yoshida, Chuhei Ogawa, Naoto Suzuki, Yasuyuki Sano, Yoshinori Kawabata

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Keywords: mixed dust pneumoconiosis, dust exposure, subacute exacerbation, silico-asbestosis, steroid therapy

JOURNAL OPEN ACCESS

2006 Volume 45 Issue 15 Pages 917-921

DOI https://doi.org/10.2169/internalmedicine.45.1656

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Abstract

A 73-year-old man with silico-asbestosis responded to steroid therapy. Chest CT scans showed diffuse micronodular opacities and ground glass opacities bilaterally throughout the entire lung fields, as well as progressive massive fibrosis in the bilateral upper lung fields. Diagnostic thoracoscopic biopsy revealed mixed dust pneumoconiosis with silicotic nodules, as well as fibrosis similar to that of Usual Interstitial Pneumonia (UIP) with many fibroblastic foci and alveolitis. Many asbestos bodies were also detected by iron staining.

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