Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Lymphoplasmacytic Infiltration of Multiple Organs with Immunoreactivity for IgG4: IgG4related Systemic Disease
Takako SaekiAkihiko SaitoTohru HiuraHajime YamazakiIwao EmuraMitsuhiro UenoSyoji MiyamuraFumitake Gejyo
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JOURNALS OPEN ACCESS

2006 Volume 45 Issue 3 Pages 163-167

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Abstract

We report three elderly men with high serum IgG4 concentrations and multiple lymphoplasmacytic inflammation of the salivary glands, lymph nodes, pancreas, and renal interstitium. The infiltrating plasma cells had strong immunoreactivity for IgG4, even in patients without pancreatic lesions. These cases show that IgG4 is associated not only with autoimmune pancreatitis, but also with other systemic lymphoplasmacytic disease.

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© 2006 by The Japanese Society of Internal Medicine
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