Adrenal Failure Caused by a Retroperitoneal Malignant Mesothelioma

Masatoshi Nomura; Hironobu Sasano; Yasuyo Okada; Tetsuhiro Watanabe; Shohei Sakamoto; Yumiko Sakiyama; Ryuichi Sakamoto; Ichiro Abe; Toshihiro Horiuchi; Toshihiko Yanase; Ryoichi Takayanagi

doi:10.2169/internalmedicine.48.2438

CASE REPORTS

Adrenal Failure Caused by a Retroperitoneal Malignant Mesothelioma

Masatoshi Nomura, Hironobu Sasano, Yasuyo Okada, Tetsuhiro Watanabe, Shohei Sakamoto, Yumiko Sakiyama, Ryuichi Sakamoto, Ichiro Abe, Toshihiro Horiuchi, Toshihiko Yanase, Ryoichi Takayanagi

Author information

Masatoshi Nomura
Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University
Hironobu Sasano
Department of Pathology, Tohoku University Graduate School of Medicine
Yasuyo Okada
Department of Social Insurance, Nakabaru Hospital
Tetsuhiro Watanabe
Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University
Shohei Sakamoto
Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University
Yumiko Sakiyama
Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University
Ryuichi Sakamoto
Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University
Ichiro Abe
Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University
Toshihiro Horiuchi
Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University
Toshihiko Yanase
Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University
Ryoichi Takayanagi
Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University

Keywords: adrenal failure, retroperitoneal mesothelioma, chemotherapy

JOURNAL OPEN ACCESS

2009 Volume 48 Issue 24 Pages 2109-2114

DOI https://doi.org/10.2169/internalmedicine.48.2438

Details

Abstract

A 62-year-old man presented with clinical signs of acute abdominal pain and adrenal insufficiency. Computerized tomographic scans revealed bilateral adrenal tumors and the left adrenal tumor was surgically resected. The patient was found to have retroperitoneal mesothelioma presenting as bilateral metastatic adrenal tumors, which were well controlled by systemic chemotherapy with CDDP and 5-FU. This case appears to be the first reported case in the literature of adrenal failure due to bilateral adrenal infiltration caused by retroperitoneal malignant mesothelioma.

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