Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Mediastinal Growing Teratoma Syndrome Succesfully Treated by Multiple Modality Therapies
Toshihiko AgatsumaTomonobu KoizumiKeishi KuboGaku SaitoRyuichi KondoKazuo YoshidaKen-ichi ItoMaki EndoHisashi Shimojo
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JOURNALS OPEN ACCESS

2011 Volume 50 Issue 6 Pages 607-610

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Abstract

A 43-year-old-man was diagnosed as having primary mediastinal nonseminomatous germ cell tumor based on pericutaneous biopsy and an elevated serum concentration of alpha-fetoprotein (AFP). Although AFP decreased after chemotherapy, the mass size grew and developed tracheal compression by the tumor. The patient was treated with mechanical ventilation and subsequent stent implantation for keeping airway patency. After three cycles of chemotherapy and normalization of AFP, the increased mass was successfully resected and the pathological examination demonstrated a mature teratoma. This case showed a rare clinical manifestation of mediastinal growing teratoma syndrome and successful outcome by multimodal therapies.

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© 2011 by The Japanese Society of Internal Medicine
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