Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Successful Treatment of Acute Promyelocytic Leukemia Accompanied by Serious Subdural Hematoma
Satoshi IchikawaTakuma SuzukiJun KimuraHideo Harigae
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JOURNALS OPEN ACCESS

2012 Volume 51 Issue 16 Pages 2209-2212

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Abstract

We present a 56-year-old woman with acute promyelocytic leukemia (APL) complicated with serious chronic subdural hematoma at presentation. She was treated with urgent hematoma evacuation and subsequent prompt chemotherapy, with administration of platelets and fresh frozen plasma. After six weeks, she achieved hematological complete remission. Thereafter she received three courses of conventional consolidation chemotherapy and achieved molecular remission. Even under conditions of severe coagulatory disturbance, aggressive therapeutic intervention including surgical procedures can save the life of a patient suffering from simultaneous APL and fatal subdural hematoma at presentation.

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© 2012 by The Japanese Society of Internal Medicine
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