Undifferentiated Carcinoma of the Pancreas Involving Intraductal Pedunculated Polypoid Growth

Shotaro Ishii; Go Kobayashi; Naotaka Fujita; Yutaka Noda; Kei Ito; Jun Horaguchi; Shinsuke Koshita; Yoshihide Kanno; Takahisa Ogawa; Kaori Masu; Shinichi Hashimoto; Takashi Sawai; Miwa Uzuki

doi:10.2169/internalmedicine.51.8779

CASE REPORTS

Undifferentiated Carcinoma of the Pancreas Involving Intraductal Pedunculated Polypoid Growth

Shotaro Ishii, Go Kobayashi, Naotaka Fujita, Yutaka Noda, Kei Ito, Jun Horaguchi, Shinsuke Koshita, Yoshihide Kanno, Takahisa Ogawa, Kaori Masu, Shinichi Hashimoto, Takashi Sawai, Miwa Uzuki

Author information

Shotaro Ishii
Departemetnt of Gastroenterology, Sendai City Medical Center, Japan
Go Kobayashi
Departemetnt of Gastroenterology, Sendai City Medical Center, Japan
Naotaka Fujita
Departemetnt of Gastroenterology, Sendai City Medical Center, Japan
Yutaka Noda
Departemetnt of Gastroenterology, Sendai City Medical Center, Japan
Kei Ito
Departemetnt of Gastroenterology, Sendai City Medical Center, Japan
Jun Horaguchi
Departemetnt of Gastroenterology, Sendai City Medical Center, Japan
Shinsuke Koshita
Departemetnt of Gastroenterology, Sendai City Medical Center, Japan
Yoshihide Kanno
Departemetnt of Gastroenterology, Sendai City Medical Center, Japan
Takahisa Ogawa
Departemetnt of Gastroenterology, Sendai City Medical Center, Japan
Kaori Masu
Departemetnt of Gastroenterology, Sendai City Medical Center, Japan
Shinichi Hashimoto
Departemetnt of Gastroenterology, Sendai City Medical Center, Japan
Takashi Sawai
Division of Leading Pathophysiology, Department of Pathology, School of Medicine, Iwate Medical University, Japan
Miwa Uzuki
Division of Leading Pathophysiology, Department of Pathology, School of Medicine, Iwate Medical University, Japan

Keywords: undifferentiated carcinoma of the pancreas, intraductal tumor, polypoid tumor, cell block method, pancreatic juice cytology

JOURNAL OPEN ACCESS

2012 Volume 51 Issue 24 Pages 3373-3377

DOI https://doi.org/10.2169/internalmedicine.51.8779

Details

Abstract

We herein report a case of pancreatic undifferentiated carcinoma involving intraductal pedunculated polypoid growth. Duodenoscopy disclosed a congested polypoid mass protruding from the orifice of the papilla of Vater. Endoscopic retrograde pancreatography (ERP) showed a polypoid lesion in Wirsung's duct and Santorini's duct. Pancreatic juice cytology using the cell block method revealed the presence of undifferentiated carcinoma. No extraductal invasion was detected on endoscopic ultrasonography and or intraductal ultrasonography. The patient therefore underwent pancreaticoduodenectomy. A histological examination revealed an intraductal polypoid tumor with a thin stalk without extraductal invasion. The tumor was composed of an abundant mixture of pleomorphic cells, spindle cells, giant cells, and a small amount of adenocarcinoma.

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