Well-differentiated Hepatocellular Carcinoma Detected as Hypovascularity by Only CT during Hepatic Arteriography

Jun Saito; Soo Ryang Kim; Masatoshi Kudo; Susumu Imoto; Kenji Ando; Taisuke Nakajima; Katsumi Fukuda; Yumi Otono; Soo Ki Kim; Takamitsu Komaki; Hirohisa Yano; Osamu Nakashima; Kayo Sugimoto; Toshiyuki Matsuoka

doi:10.2169/internalmedicine.51.6904

CASE REPORTS

Well-differentiated Hepatocellular Carcinoma Detected as Hypovascularity by Only CT during Hepatic Arteriography

Jun Saito, Soo Ryang Kim, Masatoshi Kudo, Susumu Imoto, Kenji Ando, Taisuke Nakajima, Katsumi Fukuda, Yumi Otono, Soo Ki Kim, Takamitsu Komaki, Hirohisa Yano, Osamu Nakashima, Kayo Sugimoto, Toshiyuki Matsuoka

Author information

Jun Saito
Department of Gastroenterology, Kobe Asahi Hospital, Japan
Soo Ryang Kim
Department of Gastroenterology, Kobe Asahi Hospital, Japan
Masatoshi Kudo
Department of Gastroenterology and Hepatology, Kinki University School of Medicine, Japan
Susumu Imoto
Department of Gastroenterology, Kobe Asahi Hospital, Japan
Kenji Ando
Department of Gastroenterology, Kobe Asahi Hospital, Japan
Taisuke Nakajima
Department of Gastroenterology, Kobe Asahi Hospital, Japan
Katsumi Fukuda
Department of Gastroenterology, Kobe Asahi Hospital, Japan
Yumi Otono
Department of Gastroenterology, Kobe Asahi Hospital, Japan
Soo Ki Kim
Department of Gastroenterology and Hepatology, Kyoto University, Japan
Takamitsu Komaki
Department of Internal Medicine, Saiseikai-Tondabayashi Hospital, Japan
Hirohisa Yano
Department of Pathology, Kurume University School of Medicine, Japan
Osamu Nakashima
Department of Pathology, Kurume University School of Medicine, Japan
Kayo Sugimoto
Department of Pharmacy, Kobe Asahi Hospital, Japan
Toshiyuki Matsuoka
Department of Radiology, Osaka City University Medical School, Japan

Keywords: well-differentiated hepatocellular carcinoma, imaging studies, Gd-EOB-DTPA-enhanced MRI, CT during hepatic arteriography, hypovascular tumor, Sonazoid contrast-enhanced US

JOURNAL OPEN ACCESS

2012 Volume 51 Issue 8 Pages 885-890

DOI https://doi.org/10.2169/internalmedicine.51.6904

Details

Abstract

We describe a well-differentiated hepatocellular carcinoma (HCC) with alcohol-related liver cirrhosis in a 69-year-old man. Ultrasonography (US) disclosed a 10 mm hypoechoic nodule in segment 4; Sonazoid contrast-enhanced US and gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) revealed no defect in either the Kupffer phase or the hepatobiliary phase. Computed tomography during hepatic arteriography (CTHA), however, revealed a hypovascular nodule, but CT during arterial portography showed no perfusion defect. Histological analysis indicated a well-differentiated HCC. Thus, our detection of well-differentiated HCC disclosed by only CTHA attested to the efficiency of this modality, suggesting that it is more sensitive than Gd-EOB-GTPA-enhanced MRI.

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