Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Extramedullary Hematopoietic Pleural Effusion Accompanied by Follicular Lymphoma
Naohiro SekiguchiSatoshi NotoMiyuki WagatsumaKiyoe MidorikawaShunsuke TezukaTakeshi HaginoIkuo SaitoKazuaki YamadaNaoki TakezakoAkiyoshi Miwa
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JOURNAL OPEN ACCESS

2013 Volume 52 Issue 24 Pages 2801-2804

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Abstract

Extramedullary hematopoietic effusion (EHE) is recognized to be an unusual phenomenon accompanied by hematologic disorders. Only a few reports are available of EHE occurring in patients with lymphoma. We herein report the case of a 54-year-old man with follicular lymphoma. Bone marrow aspirates and biopsied specimens showed diffuse invasion of small cleaved atypical lymphoid cells that were positive for CD10, 20, bcl2, immunoglobulin lambda and Bcl-2-IgH rearrangement. The pleural effusion aspirates and a biopsied specimen obtained via thoracoscopy revealed megakaryocytes and immature myeloid cells in addition to lymphoma cells. To the best of our knowledge, this is the first report of EHE accompanied by lymphoma according to the World Health Organization classification.

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© 2013 by The Japanese Society of Internal Medicine
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