Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
CASE REPORTS
Prolonged Disturbance of Consciousness Caused by Severe Hypophosphatemia: A Report of Two Cases
Takaaki MurakamiMasanori YoshidaTomoko FunazoYuki MatsudaKoji MatsuoTakuo NambuShin YonemitsuSeiji MuroShogo Oki
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JOURNALS OPEN ACCESS

Volume 53 (2014) Issue 19 Pages 2227-2232

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Abstract

We herein describe two patients with a prolonged disturbance of consciousness due to severe hypophosphatemia. Case one presented with pneumococcal infection and acute exacerbation of chronic obstructive pulmonary disease and asthma. Case two presented with diabetic foot infections and diabetic ketoacidosis. Both patients responded to initial therapy for their primary diseases, but consciousness became worse in both cases. Their test results for impaired consciousness revealed severe hypophosphatemia; therefore, phosphate replacement therapy was administered, thus resulting in complete alertness. These cases demonstrate that we should consider the possibility of hypophosphatemia in critically ill patients with an altered consciousness.

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© 2014 by The Japanese Society of Internal Medicine
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