Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Gastric Mixed Adenoneuroendocrine Carcinoma with a Good Prognosis
Nobuhiko FukubaTakafumi YukiShunji IshiharaHiroki SonoyamaYasumasa TadaRyusaku KusunokiAkihiko OkaNaoki OshimaIchiro MoriyamaKousaku KawashimaYoshikazu Kinoshita
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JOURNALS OPEN ACCESS

2014 Volume 53 Issue 22 Pages 2585-2588

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Abstract

A flat, elevated lesion measuring 5 mm in diameter was found in the gastric body of an 80-year-old man. A biopsy showed moderately differentiated adenocarcinoma, and endoscopic ultrasonography revealed a hypoechoic mass located in the submucosa. Endoscopic submucosal dissection was subsequently performed, and a pathological examination revealed a tumor composed of adenocarcinoma and neuroendocrine carcinoma with submucosal infiltration. The pathological diagnosis was gastric mixed adenoneuroendocrine carcinoma (MANEC). An additional gastrectomy procedure was performed, and no recurrence was noted for at least three years. This case is interesting with respect to the carcinogenesis of endocrine cell carcinoma and MANEC.

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© 2014 by The Japanese Society of Internal Medicine
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