Successful Multidisciplinary Therapy for Small Cell Carcinomas Arising from the Extrahepatic Bile Duct

Koh Nakamaru; Tsukasa Ikeura; Hideaki Miyoshi; Makoto Takaoka; Naoyuki Danbara; Shunsuke Horitani; Masataka Masuda; Yasutaka Yamada; Yoshiko Uemura; Hideyoshi Toyokawa; Sohei Satoi; A-Hon Kwon; Kazuichi Okazaki

doi:10.2169/internalmedicine.54.4603

CASE REPORTS

Successful Multidisciplinary Therapy for Small Cell Carcinomas Arising from the Extrahepatic Bile Duct

Koh Nakamaru, Tsukasa Ikeura, Hideaki Miyoshi, Makoto Takaoka, Naoyuki Danbara, Shunsuke Horitani, Masataka Masuda, Yasutaka Yamada, Yoshiko Uemura, Hideyoshi Toyokawa, Sohei Satoi, A-Hon Kwon, Kazuichi Okazaki

Author information

Koh Nakamaru
The Third Department of Internal Medicine, Kansai Medical University, Japan
Tsukasa Ikeura
The Third Department of Internal Medicine, Kansai Medical University, Japan
Hideaki Miyoshi
The Third Department of Internal Medicine, Kansai Medical University, Japan
Makoto Takaoka
The Third Department of Internal Medicine, Kansai Medical University, Japan
Naoyuki Danbara
The Third Department of Internal Medicine, Kansai Medical University, Japan
Shunsuke Horitani
The Third Department of Internal Medicine, Kansai Medical University, Japan
Masataka Masuda
The Third Department of Internal Medicine, Kansai Medical University, Japan
Yasutaka Yamada
The Third Department of Internal Medicine, Kansai Medical University, Japan
Yoshiko Uemura
Department of Pathology, Kansai Medical University Hirakata Hospital, Japan
Hideyoshi Toyokawa
Department of Surgery, Kansai Medical University, Japan
Sohei Satoi
Department of Surgery, Kansai Medical University, Japan
A-Hon Kwon
Department of Surgery, Kansai Medical University, Japan
Kazuichi Okazaki
The Third Department of Internal Medicine, Kansai Medical University, Japan

Keywords: bile duct cancer, small cell carcinoma, chemotherapy, radiotherapy

JOURNAL OPEN ACCESS

2015 Volume 54 Issue 21 Pages 2711-2715

DOI https://doi.org/10.2169/internalmedicine.54.4603

Details

Abstract

A 74-year-old man was diagnosed with small cell carcinoma arising from the extrahepatic bile duct according to a histological examination of the biopsy specimen obtained during endoscopic retrograde cholangiopancreatography. Additionally, bulky hilar lymphadenopathy was observed, and the patient was treated with the combination of radiation and chemotherapy (cisplatin and irinotecan). Post-therapy, he underwent pancreaticoduodenectomy. The histological examination of the resected specimen revealed no residual cancer cells in the bile duct wall and a small amount of cancer cells in only a single lymph node. Due to this multidisciplinary therapy, the patient showed no signs of recurrence 12 months postoperatively.

Corresponding author

Register with J-STAGE for free!