Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Treatment of Class IV Lupus Nephritis with Mycophenolate Mofetil Monotherapy
Takashi NawataMakoto KuboShohei FujiiKosaku ShiragamiTadayoshi IkegamiShigeki KobayashiSatoshi HisanoMasafumi Yano
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JOURNALS OPEN ACCESS

2018 Volume 57 Issue 14 Pages 2067-2070

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Abstract

Lupus nephritis (LN) occurs in up to 60% of systemic lupus erythematosus patients. Combination therapy involving a corticosteroid and cyclophosphamide or mycophenolate mofetil (MMF) has been a standard therapy for LN. However, clinicians generally prefer to minimize steroid use in LN treatment. We herein report the case of a Japanese man with LN whose severe chronic heart failure prevented us from using steroid therapy. Instead, his LN was successfully treated with MMF monotherapy. Based on our experience with this case, we suggest that MMF monotherapy may represent a feasible LN treatment option in patients who cannot tolerate steroid therapy.

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© 2018 by The Japanese Society of Internal Medicine
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