Gastric Adenocarcinoma of the Fundic Gland Type after Endoscopic Therapy for Metachronous Gastric Cancer

Hitoshi Kino; Masakazu Nakano; Akira Kanamori; Tsunehiro Suzuki; Yoshihito Kaneko; Chieko Tsuchida; Kouhei Tsuchida; Keiichi Tominaga; Takako Sasai; Hidetsugu Yamagishi; Yasuo Imai; Hideyuki Hiraishi

doi:10.2169/internalmedicine.9359-17

CASE REPORTS

Gastric Adenocarcinoma of the Fundic Gland Type after Endoscopic Therapy for Metachronous Gastric Cancer

Hitoshi Kino, Masakazu Nakano, Akira Kanamori, Tsunehiro Suzuki, Yoshihito Kaneko, Chieko Tsuchida, Kouhei Tsuchida, Keiichi Tominaga, Takako Sasai, Hidetsugu Yamagishi, Yasuo Imai, Hideyuki Hiraishi

Author information

Hitoshi Kino
Department of Gastroenterology, Dokkyo Medical University, Japan
Masakazu Nakano
Department of Gastroenterology, Dokkyo Medical University, Japan
Akira Kanamori
Department of Gastroenterology, Dokkyo Medical University, Japan
Tsunehiro Suzuki
Department of Gastroenterology, Dokkyo Medical University, Japan
Yoshihito Kaneko
Department of Gastroenterology, Dokkyo Medical University, Japan
Chieko Tsuchida
Department of Gastroenterology, Dokkyo Medical University, Japan
Kouhei Tsuchida
Department of Gastroenterology, Dokkyo Medical University, Japan
Keiichi Tominaga
Department of Gastroenterology, Dokkyo Medical University, Japan
Takako Sasai
Department of Gastroenterology, Dokkyo Medical University, Japan
Hidetsugu Yamagishi
Department of Diagnotic Pathology, Dokkyo Medical University, Japan
Yasuo Imai
Department of Diagnotic Pathology, Dokkyo Medical University, Japan
Hideyuki Hiraishi
Department of Gastroenterology, Dokkyo Medical University, Japan

Keywords: gastric adenocarcinoma of fundic gland type, Helicobacter pylori, endoscopic submucosal dissection

JOURNAL OPEN ACCESS

2018 Volume 57 Issue 6 Pages 795-800

DOI https://doi.org/10.2169/internalmedicine.9359-17

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Abstract

A 78-year-old man underwent endoscopic submucosal dissection (ESD) for early gastric adenocarcinoma twice in 2009 and 2014. Between the procedures, he successfully completed Helicobacter pylori eradication therapy. In May 2015, upper endoscopy screening showed two elevated lesions on the gastric fundus, and en bloc resection by ESD was performed. We histopathologically diagnosed the patient to have gastric adenocarcinoma of the fundic gland type. In this case, the two lesions of gastric adenocarcinoma of the fundic gland type multifocally developed after ESD for metachronous gastric tubular adenocarcinoma. Furthermore, they appeared in the gastric fundus, where atrophy had been improved due to eradication therapy.

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