Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Effect of Lansoprazole on the Control of the Intragastric pH in a Patient with Short Bowel Syndrome
Masato YoshiokaTasuku WatanabeMasatake IidaYasuhiko NakagawaHiroshi UchinamiGo WatanabeYuki AbeFumitaka YagiNaohiro YokoyamaYuzo Yamamoto
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JOURNAL OPEN ACCESS

2019 Volume 58 Issue 12 Pages 1723-1726

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Abstract

A 40-year-old man suffered from short bowel syndrome. Since a large amount of intestinal output and watery diarrhea hampered his quality of life, we tried to control the intestinal output by reducing the secretion of gastric acid with lansoprazole. Because the small intestine was only 10 cm in length and effective absorption of oral lansoprazole was doubtful, we monitored his intragastric pH for 24 hours and confirmed that the holding time above pH 3.0 was 14.5 hours (60.4%). He spent his home life eating porridge during the day, and receiving total parenteral nutrition of 1,100 mL/day at night while taking lansoprazole as an oral tablet (30 mg) once a day.

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© 2019 by The Japanese Society of Internal Medicine
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