Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
A Favipiravir-induced Fever in a Patient with COVID-19
Takashi KuritaKeiko IshidaEmiri MuranakaHiroki SasazawaHaruki MitoYudai YanoRyota Hase
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JOURNAL OPEN ACCESS

2020 Volume 59 Issue 22 Pages 2951-2953

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Abstract

We herein report the first case of a fever induced by favipiravir, a potential coronavirus disease 2019 therapeutic drug. An 82-year-old man diagnosed with bilateral pneumonia was transferred to our hospital following a positive severe acute respiratory syndrome coronavirus 2 polymerase chain reaction test. He was treated with compassionate use of favipiravir. Both his oxygen demand and fever gradually improved after admission; however, his fever relapsed, and the C-reactive protein (CRP) levels increased on day 7. We diagnosed his fever as being favipiravir-induced. The fever resolved a few days after favipiravir discontinuation, demonstrating the accuracy of the diagnosis. This case revealed that favipiravir can induce a fever.

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© 2020 by The Japanese Society of Internal Medicine
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