Use of Nasopancreatic Drainage for Severe Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis: A Case Series

Shinya Kawaguchi; Masataka Kikuyama; Tatsunori Satoh; Shuzo Terada

doi:10.2169/internalmedicine.0549-17

This article has now been updated. Please use the final version.

Use of Nasopancreatic Drainage for Severe Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis: A Case Series

Shinya Kawaguchi, Masataka Kikuyama, Tatsunori Satoh, Shuzo Terada

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Keywords: nasopancreatic drainage, severe post-endoscopic retrograde cholangiopancreatography pancreatitis, proteinase-activated receptor-2

JOURNAL OPEN ACCESS Advance online publication

Article ID: 0549-17

DOI https://doi.org/10.2169/internalmedicine.0549-17

The final version of this article is now available: Vol. 57 (2018), No. 18 pp. 2657-2662

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Abstract

Five patients complaining of severe pain due to severe post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) underwent nasopancreatic drainage (NPD) placement. Pain relief was achieved on the second, fourth, and fifth day in three, one, and one patients, respectively. Four patients underwent pancreatic juice culture; all were positive. Our results suggest that NPD can relieve severe PEP with severe pain. Bacteria-induced protease-activated receptor-2 activation may be associated with PEP.

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